House takes on a case of a patient with two different personalities as a result of having the left and right part of the brain operating independently. Meanwhile, he deals with the aftermath of his night of sex with Cuddy.

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While House tries to cope with his insomnia, he takes on the case of a ballerina whose skin begins to fall off after treatment following the collapse of her lungs during a performance.

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A deaf 14-year old wrestler suffers from hearing problems during a match, but his mother refuses to okay cochlear implants. Meanwhile, House’s insomnia proves a curse… and a blessing.

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Cameron postpones her vacation with Chase to take on the case of an environmentalist who collapsed in the middle of a protest. Meanwhile, House wonders why Wilson is starting a new healthy diet.

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The team deals with an older woman who has been tending to her dying husband but is stricken down with an unknown disease that threatens to kill her before her husband. However, they must overcome their own emotions when a tragedy strikes one of their members.

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